Directories
Xu Lu, Ph.D.

Xu Lu, Ph.D.

Assistant Professor of Biology
Year started at UF: 2010
Contact Information
Office Location: Davis Street Building Room 1134
Telephone: 419-434-5614
Credentials
B.S., Biochemistry, Peking University (北京大学),
Ph.D., Biochemistry, The University of Texas Health Science Center at San Antonio, 2004

  • Academic Credentials:

    Doctor of Philosophy in Biochemistry from the University of Texas Health Science Center

    Bachelor of Science in Biochemistry/Molecular Biology from Peking University


    Additional Information:

    Dr. Xu Lu obtained his B.S. degree from Peking University and his Ph.D. degree from the University of Texas Health Science Center at San Antonio. At University of Findlay, Dr. Lu teaches a variety of lectures and labs, including Introduction to Cell and Molecular Biology (BIOL 152) and its Laboratory (BIOL 152L), Human Genetics (BIOL 310) and its Laboratory (BIOL 310L), Cell Biology (BIOL 302), Immunology (BIOL 300), Basic Environmental Toxicology (BIOL 405), Special Investigation (BIOL 422) and Senior Biology Seminar (BIOL 498).

    Dr. Lu’s research interests include cancer biology, computational biology and epidemiology. Students interested in his research projects should contact Dr. Lu ([email protected]) directly for additional information.

  • Peer-reviewed articles: 

     

    Botting, C., Lu, X., and Triezenberg, S.J. (2015) H2AX Phosphorylation and DNA Damage Kinase Activity are Dispensable for Herpes Simplex Virus Replication. Submitted to Virology.


    Zhang, X., Zhang, Z., Lu, X., Yang, P., Cai, M., Hu, W., Yun, J., Zhou, F., Qian, C., and Cao, Y.(2015) Prognostic significance of preoperative serum lactate dehydrogenase in upper urinary tract urothelial carcinoma.  Submitted to Clin Genitourin Cancer.


    Prater, K.J., Fortuna, C.A., Gcgill, J.L., Brandeberry, M.S., Stone, A.R., and Lu, X. (2015) Poor Hand Hygiene by College Students Linked to More Occurrences of Infectious Diseases, Medical Visits and Absence from Classes. In press at Am. J. Infect. Control.

    Muthurajan, U.M., McBryant, S.J., Lu, X., Hansen, J.C., and Luger, K. (2011) The linker region of macroH2A promotes self-association of nucleosomal arrays. J. Biol. Chem. 286:23852-23864.

    Lu, X., and Triezenberg, S.J. (2010) Chromatin assembly on herpes simplex virus genomes during lytic infection. Biochim. Biophys. Acta. 1799: 217-222.

    Lu, X., Parseghian, M.H., Hamkalo, B.A., and Hansen, J.C. (2009) Chromatin condensing functions of the linker histone C-terminal domain are mediated by specific amino acid composition and intrinsic protein disorder. Biochemistry 48: 164-172.

    Lu, X., Simon, M.D., Chodaparambil, J.V., Hansen, J.C., Shokat, K.M., and Luger, K. (2008) The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure. Nat. Struct. Mol. Biol. 15: 1122-1124.

    Chodaparambil, J.V., Barbera, A.J., Lu, X., Kaye, K., Hansen, J.C., and Luger, K. (2008) A charged and contoured surface on the nucleosome regulates chromatin compaction. Nat. Struct. Mol. Biol. 14: 1105-1107.

    Kan, P.-Y., Lu, X., Hansen, J.C., and Hayes, J.J. (2007) The H3 tail domain mediates interactions between self-associating nucleosome arrays. Mol. Cell Biol. 27, 2084-2091.

    Lu, X., Klonoski, J.M., Resch, M.G., and Hansen, J.C. (2006) In vitro chromatin self-association and its relevance to genome architecture. Biochem. Cell Biol. 84, 411-417. Hansen, J. C., Lu, X., Ross, E. D. and Woody, R. W. (2006) Intrinsic protein disorder, amino acid composition, and histone terminal domains. J. Biol. Chem. 281, 1853-1856.

    Widlak, P., Kalinowska, M., Parseghian, M.H., Lu, X., Hansen, J.C., and Garrard, W.T. (2005) The Histone H1 C-terminal Domain Binds to the Apoptotic Nuclease, DNA Fragmentation Factor (DFF40/CAD) and Stimulates DNA Cleavage. Biochemistry 44, 7871-7878.

    Zheng, C., Lu, X., Hansen, J. C. and Hayes, J. J. (2005) Salt-dependent intra- and internucleosomal interactions of the H3 tail domain in a model oligonucleosomal array. J. Biol. Chem. 280, 33552-33557.

    Lu, X., and Hansen, J.C. (2004) Identification of specific functional subdomains within the linker histone H1º C-terminal domain. J. Biol. Chem. 279, 8701-8707.

    Lu, X., and Hansen, J.C. (2003) Revisiting the structure and functions of linker histone C-terminal tail domain. Biochem. Cell Biol. 81,173-176.

    Awarded and referred presentations

    Eck, J., Meek, N., Lauer, L., Culbert, M.D., Koch, C., Spath, R., Schneider, H., and Lu, X. (2012) Development of a software package to analyze protein intrinsic disorder. The Consortium for Computing Sciences and Colleges Midwest Conference, Charleston, Illinois. Third Place Poster Award

    Stone, A.R., Brandeberry, M.S., Culbert, R., and Lu, X. (2014) Effect of caffeine on cancer cell growth. Tri-beta Northeastern Region District IV Annual Convention, Findlay, Ohio. Second Place in the John C. Johnson Award for Excellence in Student Research

    Brandeberry, M.S., Stone, A.R., Capestrain, M., Culbert, R., and Lu, X. (2015) Effect of bitter melon juice on cancer cell growth. Tri-beta Northeastern Region District IV Annual Convention, Crestview Hills, Kentucky. Honorable Mention in the John C. Johnson Award for Excellence in Student Research